EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (Under Process) , 

 ISSN 2394-3211

Impact Factor: 4.897

 ICV - 79.57

Abstract

STUDY OF THE STATE OF THE IMMUNORAACTIVITY OF THE ORGANISM OF CHILDREN WITH A NASOPHARYNGEAL CANCER

*Polatova D. S., Karimova N. M., Ismailova A. A., Hayitov F. E., Iskandarova I. M., Nuriddinov K. R., Boboev M. M., Hayitova A. T. and Abdukhakimova M.

ABSTRACT

The purpose of this work was to study the state of immunoreactivity in children with nasopharyngeal cancer. Proceeding from the received results it is visible, that at a cancer of a nasopharynx at children the expressed unbalance cellular and humoral parts of immune system is observed. Imbalance in the cellular immunity unit was expressed in the suppression of the immunoregulatory index due to a decrease in the number of T-helpers / inducers and an increase in T-cytotoxic lymphocytes. Circulating immune complexes of large and small values were increased. Consequently, the role of immunological factors in the formation and flow of nasopharyngeal cancer in children is indicated by various changes in the state of immunoreactivity. Obviously, the T-cell response is much weaker and is directed against a smaller number of tumor epitopes, which suggests that clonal depletion of T-lymphocytes is possible against the background of activation of some humoral immunity factors.

Keywords: Nasopharyngeal cancer in children, adaptive immune response, lymphocytes, cellular immunity factors, immunoglobulins.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (Under Process)