EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (Under Process) , 

 ISSN 2394-3211

Impact Factor: 4.897

 ICV - 79.57

Abstract

CONTRIPUTION STUDY TO THE CHEMICAL COMPOSITION OF THE RUMEX CRISPUS L. FAMILY POLYGONACEAE, WIDE SPREAD IN EUPHRAT REGION IN SYRIA, AND DETERMINATION OF THE ANTI-PROTOZOA ACTIVITY

MHD Isam Hasan Agha*

ABSTRACT

Rumex crispus L. Family Polygonaceae is widely spread plant in the Euphrates region in Syria, where is make a big trouble for the farmer and viliger in this region. We conducted this study to find out the benefits of this plant, by determination the main phenolic components in the aerial parts and the anti oxidant and anti leishmania activity. The samples of Rumex crispus were obtained from the Euphrat river by the city of Alraqqa in north east of Syria, dried and the phenolic compounds were extracted with ethanol 80% using soxhlet extraction method. The extracts was concentrated, the main phenolic compounds were detected using chromatographic methods and general reagents for phenols. Total phenolic compounds evaluated using Folin-Ciocalteu method. The Anti oxidant activity was determined using β-carotene bleaching method. Anti leishmania activity is estimated on isolates from pathogenic leishmania prepared from public health laboratories and Hospital of Dermatology in Damascus, where determnined the anti leishmania activity. In this study, found that the main phenolic components present the extracts were flavonoids, anthraquinones in the free and combeined state, and high concentration of chlorogenic acid and other organic acids. The percentage of the phenolic compounds was 6.3% and 1.7% (ether extract and ethyl acetate extract). The anti oxidant activity was 94.5% and 22.1% in both extracts. The anti Leishmania activity was determined in both extracts but the the ethylacetat extracts showed higher activity against growth of leishmania than the ether extract.

Keywords: Rumex crispus L., phenolic compounds, anti oxidant activity, anti Protozoa activity.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (Under Process)