EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (Under Process) , 

 ISSN 2394-3211

Impact Factor: 4.897

 ICV - 79.57

Abstract

SERUM GAMMA GLUTAMYL TRANSFERASE ACTIVITY IN PATIENTS WITH CARDIOVASCULAR DISEASES ASSOCIATED WITH DIABETIC MELLITUS

Ravoori Saideswar Rao* and Vanita Lal**

ABSTRACT

Back ground: Gamma glutamyl tranaferase(GGT) is a widely used marker for liver function and is correlated with alcohol intake. An increase GGT activity is linked with influx of GGT–carrying Lipoproteins into plaque. Materials and Methods: The study design is a cross sectional study with 280 participants consisting of a 3 groups. Group-1 Cardiovascular disease (CVD) without diabetes,Group-2 CVD with diabetes,Group-3 Healthy individuals. The analysis of GGT, RBS, lipid profile ,SGOT and SGPT were done in central hospital laboratory of SRMC&RI by using standard kits in Dimension RxL autoanalyser. The results were expressed as mean ±SD.The data analysis was done by using ANOVA and Pearson’s correlation. Result: We observed a statistically significant increase (p ˂ 0.001) in serum GGT levels in group 1& 2 compared to group 3. There is no statistically significant in serum GGT levels in cardiovascular disease with diabetes and without diabetes. There is good significant correlation between the GGT with total cholesterol(r = 1). A week correlation was obtained between GGT and triglycerides, LDL and negatively correlated with HDL. Conclusion: Higher Gamma glutamyl transferase levels are associated to cardiovascular disease in people with and without diabetes.There is increased concentration of GGT in serum compared to healthy individuals.

Keywords: Gamma Glutamyl Transferase, Oxidative Stress, Atherosclerosis, Cardiovascular Disease.


[Full Text Article]

INDEXING

NEWS & UPDATION

  • New Issue Published

    Its Our pleasure to inform you that, EJPMR 1 October 2018 Issue has been Published, Kindly check it on http://www.ejpmr.com/home/current_issues

  • EJPMR OCTOBER ISSUE PUBLISHED

    OCTOBER 2018 Issue has been successfully launched on 1 October 2018

  • EJPMR New Impact Factor

    Its our Pleasure to Inform you that EJPMR Impact Factor has been increased from 4.161 to 4.897 due to high quality Publication at International Level

  • Index Copernicus Value

    EJPMR Received Index Copernicus Value 79.57, due to High Quality Publication in EJPMR at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Article are invited for publication in EJPMR Coming Issue

Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (Under Process)