EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (Under Process) , 

 ISSN 2394-3211

Impact Factor: 4.897

 ICV - 79.57

Abstract

THE INFLUENCE OF SOME ENVIRONMENTAL POLLUTANTS ON THE HISTOGENESIS OF TEETH IN EXPERIMENTAL RATS

Kamilov Kh. P.* and Taylakova D. I.

ABSTRACT

The purpose of the work was to identify the features of embryonic development of rats as a whole, as well as embryonic and postnatal development of their dentoalveolar system under conditions of intrauterine exposure to some chemicals polluting the environment. Pesticides, hexachlorane and fosalone, as well as sulfur dioxide and nitrogen dioxide, which are the main components of harmful emissions from oil refineries, have been selected as polluting chemicals. The experiments were performed on non-matured mature white female rats with a body weight of 170-180 g.It is found that prenatal exposure of toxic substances (pesticides, sulfur and nitrogen dioxides) leads to impaired fetal and postnatal development of offspring, which are shown to the maximum extent in combined toxicity of pesticides and dioxides. It was also revealed that combined intrauterine intoxication substantially interferes with the tooth tissue differentiation and jaw bones of the fetus, resulting in the delayed eruption and abnormal development of the teeth in the postnatal period. Combined intrauterine intoxication significantly violates the processes of tissue differentiation of dental germ and ossification of the jaw bones of the fetus, which result in delayed eruption and abnormal development of teeth in the postnatal period.

Keywords: pesticides, dioxins, embryonic development, developmental dental toxicity, dental histogenesis, environmental toxicants.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (Under Process)