EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (Under Process) , 

 ISSN 2394-3211

Impact Factor: 4.897

 ICV - 79.57

Abstract

ANTIMICROBIAL EFFECT OF ALMISWAK (SALVADORA PERSICA LINN) EXTRACTS, AGAINST SELECTED PATHOGENIC MICROBES

Huda Manna Alamri, Dr. Sarah Ali* and Dr. Nadia Hashish

ABSTRACT

Introduction: Oral hygiene is one of the most important daily routine practices and keeps the mouth and teeth clean. In the Muslim world, the use of Miswak as a chewing stick is highly recommended as a Sunnah practiced by the prophet Mohammad (peace be upon him).This study was designed to scientifically establish antimicrobial effect of Miswak in vitro against some pathogenic microorganisms. Methodology: An experimental study design method was conducted in Qassim University Microbiology Laboratory. The twigs of S.persica were collected and alcoholic and hexane extracts were prepared using standard techniques. The antimicrobial properties of the extracts against Staphylococcus aureus, Psuedomonas aeruginosa, Candida albicans were tested by agar well diffusion method. Result: Different concentrations of Alcoholic extract 100 mg/ml, 50 mg/ml, 25 mg/ml and 12.5 mg/ml the tested bacteria showed no zone of inhibition. When the same organisms were subjected to Hexan extracts of similar concentrations, significant zone of inhibition was noted particularly with 100 mg/ml concentration. Comparing the inhibition zone of S. aureus, P.aeruginosa and C.albicans, the 100 mg/ml concentration of hexan extract was more effective against P. aeruginosa producing 62.5mm inhibition zone as compared of 60mm inhibition zone against C.albicans and 40mm inhibition zone against S.aureus. Conclusion: Hexane extracts of S. persica was found to exhibit antimicrobial activity against S.aurus, P.aeruginosa and C.albicans at high concentration and lower concentration while alcoholic extract of miswak show no inhibitory effect against the same microorganisms.

Keywords: Almiswak, Salvadora persica linn, Antimicrobial activity, S.aureus, P.aeruginosa, C.albicans.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (Under Process)