EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (Under Process) , 

 ISSN 2394-3211

Impact Factor: 4.897

 ICV - 79.57

Abstract

EFFECT OF ADD ON SUBLINGUAL VITAMIN D3 ON SYSTOLIC AND DIASTOLIC BLOOD PRESSURE IN PATIENTS OF HYPERTENSION ON ANTIHYPERTENSIVE TREATMENT

Sanjeeva Kumar Goud T.*, Dr. Rahul Kunkulol and Dr. Sandeep Narwane

ABSTRACT

Introduction: The aim of present study was to study effects of Sublingual Vitamin D3 on blood pressure of hypertensive patients on antihypertensive drugs. Methods: This study was Non-Randomized Clinical Trail, in which 110 Hypertensive Patients participated in the study, of which, 55 each were enrolled in Test and Control Group each. All the hypertensive patients visiting the Medicine OPD of Pravara Rural Hospital, Loni, of age between 18-60 years and either gender, willing to participate in study were included in the study. Patients on thiazide diuretics or on any other chronic medications other than antihypertensives were excluded from the study. After taking written informed consent of the study participants, the patients were assigned into Test group and Control group. The participants in the test group were given add on therapy of Sublingual vitamin D3 60,000IU every 15 days for 3 months and their blood pressure was measured. Results: There was statistically significant difference reduction in systolic blood pressure from baseline visit (134±13 mm of Hg) in comparison with Visit II, V, VI and VII (ANOVA with post hoc Tukey test). Also, there was significant reduction in systolic blood pressure when Visit II, III, and IV were compared with Visit VII. Statistically significant difference was seen on comparison of systolic blood pressure of participant in Test group with that of Control group during Visits II (P<0.05, Unpaired t test), IV, V, VI and VII (P<0.05, Mann-Whitney Test). Conclusion: Sublingual Vitamin D3 therapy causes average fall in systolic blood pressure of 15 mm of Hg. Sublingual Vitamin D3 may have an add on therapeutic role in treatment of hypertension.

Keywords: Sublingual Vitamin D3,Blood pressure,Hypertensive patients.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (Under Process)