EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (Under Process) , 

 ISSN 2394-3211

Impact Factor: 4.897

 ICV - 79.57

Abstract

CHARACTERIZATION OF PATHOGENS CAUSING VENTILATOR ASSOCIATED PNEUMONIA IN INTENSIVE CARE UNITS OF A TERTIARY CARE HOSPITAL – A PROSPECTIVE STUDY

*Dr. Roshni Agarwal, Dr. Anjali Tiwari, Dr. Parvati Upadhayay, Dr. Vaibhav Agarwal, Dr. Devendra Kumar Niranjan and Dr. Niti Bhai

ABSTRACT

Introduction: Ventilator-associated pneumonia (VAP) is the most common healthcare associated infection diagnosed in intensive care units (ICUs). It is caused mostly by potentially drug-resistant bacteria. Aims and objectives: The current study aimed at determining the bacteriological etiology of VAP and antimicrobial susceptibility pattern of the isolates causing VAP in the ICUs of our hospital. Material and Methods: A prospective study was carried out from January 2017 to December 2017 from ICUs of Regency hospital, Kanpur. A total of 135 lower respiratory tract samples (Endotracheal aspirate (ETA) and Transtracheal aspirate (TTA)) of patients on Mechanical ventilator (MV) suspicious of having VAP were received in Microbiology Department and processed. Organisms were isolated by standard microbiological techniques. The isolates were then subjected to identification and antimicrobial susceptibility testing using VITEK 2 – compact. RESULTS: The majority of bacterial isolates causing VAP were found to be Gram negative bacilli (95%). Acinetobacter baumanii accounted for 60.0% followed by Klebsiella pneumoniae 22.2%, Pseudomonas aeruginosa 8.9%. Other isolates were Escherichia coli, Enterobacter cloacae & S. aureus. Out of the 39 VAP cases, 17(43.6%) were categorized under early onset VAP (<96 hrs. on MV) and 22 (56.4%) under late onset VAP (>96 hrs. on MV). Polymicrobial growth was seen in 15.4% of VAP cases. Thirty-seven (82.2%) of the 45 VAP pathogens in our study were multi-drug resistant (MDR). Conclusions: Most of the pathogens causing VAP in our institute were multidrug resistant. Colistin and Tigecycline were found to be highly effective against multidrug resistant Acinetobacter baumanii and Klebsiella pneumoniae. The bacteriological approach for the management of VAP helps the clinicians in choosing the appropriate antibiotics.

Keywords: Ventilator-associated pneumonia, Intensive care unit, Multi Drug resistant.


[Full Text Article]

INDEXING

NEWS & UPDATION

  • New Issue Published

    Its Our pleasure to inform you that, EJPMR 1 October 2018 Issue has been Published, Kindly check it on http://www.ejpmr.com/home/current_issues

  • EJPMR OCTOBER ISSUE PUBLISHED

    OCTOBER 2018 Issue has been successfully launched on 1 October 2018

  • EJPMR New Impact Factor

    Its our Pleasure to Inform you that EJPMR Impact Factor has been increased from 4.161 to 4.897 due to high quality Publication at International Level

  • Index Copernicus Value

    EJPMR Received Index Copernicus Value 79.57, due to High Quality Publication in EJPMR at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Article are invited for publication in EJPMR Coming Issue

Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (Under Process)