EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (Under Process) , 

 ISSN 2394-3211

Impact Factor: 4.897

 ICV - 79.57

Abstract

MOLECULAR CHARACTERIZATION OF FMD VIRUS DURING 2016-2017 IN EGYPT

Mahmoud Abd Algayed, Emad Elgendy, Naglaa Hagag, Momtaz Shahin and Madiha Salah Ibrahim*

ABSTRACT

Foot and Mouth Disease have an extremely contagious nature with high exceptional economic losses making FMD of a primary animal health concern. In this study, we aimed to detect and characterize FMDV in Egypt. Totally, 135 out of 785 samples (37/341 (10.85%) and 98/444 (22.1%) in 2016 and 2017; respectively, were detected from clinically infected animals from different Egyptian governorates by ELIZA test. Ten positive samples were molecularly characterized by RT-PCR, the results showed and confirmed that these animals were infected with FMDV serotype A (16.3%), O (79.3%) and SAT2 (4.4%). Only two samples could be isolated on the BHK-21 cell culture and were of serotype O. Three samples representing serotype A, O and SAT2 were sequenced and phylogenetically analyzed for the VP1 gene. The results showed that serotype O virus was closely related to O/Ismalia/2016, whereas serotype A virus was closely related to A/Fayoum/2013, and serotype SAT2 virus was closely related to SAT2/Kal/2014. These results reported the characterization of FMDV strains that co-circulated in cattle and buffalo in Egypt during 2016-2017, revealing that vaccination strategies should be reviewed aiming to effective protection of farm animals. Furthermore, FMDV serotype O was the predominant strain that continuously circulated in Egypt during 2016-2017.

Keywords: FMDV, ELISA, Phylogenetic analysis, Africa, Egypt.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (Under Process)