EXTRACTION, ISOLATION AND CHARACTERIZATION OF CHARANTIN FROM MOMORDICA CHARANTIA FRUIT LINN.
Nirupama K. V.*, J. Adlin Jino Nesalin and T. Tamizh Mani
The bitter melon (L), commonly referred as bitter gourd, karela, and balsam pear. Its fruits are used for the
treatment of Diabetus and related conditions amongst the indigenous populations of Asia, South America, India
and east Africa. The present study deals with an extraction, isolation and characterization of Charantin from
Momordica charantia. The Charantin is going to extract and isolated by using following methods like soxhlet
extraction, aqueous two phase method and reflux condenser method, and the isolated compound was identified by
using TLC, UV-Visible spectrophometric method, by melting point analysis and FTIR Spectroscopy. And
concluded that the yield of Charantin is more in reflux condenser method than other methods and Charantin is
having antidiabetic activity as more potent like insulin hence can be employed as antidiabetic drug further
evaluated clinically for formulating Charantin.
Keywords: Momordica charantia, Charantin, extraction and isolation, characterization.
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