EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (Under Process) , 

 ISSN 2394-3211

Impact Factor: 4.897

 ICV - 79.57

Abstract

STUDY OF THE ENZYME AND HISTOPATHOLOGICAL EFFECTS OF CHROMIUM III CHLORIDE IN THE FRESH WATER FISH CIRRHINUS MRIGALA

E. Dhanalakshmi and Pawlin Vasanthi Joseph*

ABSTRACT

Metals occur naturally in the earth‟s crust, and their contents in the environment can vary between different regions resulting in spatial variations of back ground concentrations. With the advent of rapid industrialization, urbanization and other developmental activities, most of the water sources are becoming contaminated and causing deleterious effects on aquatic bio-systems. The aim of the present work is to study the enzyme and histopathological effects of Chromium III chloride in the fresh water fish Cirrhinus mrigala. The LC50 at 96 hours was determined by the Probit Analysis Method. The experiment was designed to expose the fish to different sub chronic doses of Chromium III chloride. One trough served as control and four experimental troughs were maintained. Each trough was provided with 34mg/l, 36mg/l, 38mg/l and 40mg/l of chromium III chloride. Each trough contained ten fishes and the experiment was conducted in triplicate. The duration of the experiment was for 30 days. Enzymes were estimated after 30 days and the histopathology of the liver and muscle was studied. A significant decrease was observed in the levels of Alkaline phosphatase, Acid phosphatase, Lipase and Amylase. Histopathology studies showed degeneration in the liver and muscle. Most of the heavy metals are present in the edible portion of the fish. Humans may also be affected by eating fish and this can cause a few health problems.

Keywords: Chromium III chloride, Probit analysis, alkaline phosphatase, acid phosphatase, Lipase, Amylase, histopathology, LC 50.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (Under Process)