EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (Under Process) , 

 ISSN 2394-3211

Impact Factor: 4.897

 ICV - 79.57

Abstract

EVALUATION OF LIVER AND HAEMATOLOGICAL VARIABLES AMONG ALCOHOLICS IN JOS METROPOLIS, NORTH CENTRAL NIGERIA

Essien U. C.*, Nyam A. N., Ekwempu A. I., Kopkuk E. D., Idoko E., Sheyin Z.

ABSTRACT

The association of alcohol consumption with liver and haematopoietic function was recognized more than two centuries. Several studies have reported the effect of alcohol abuse on liver and hematological variables. We conducted this study to assess the changes in liver and Full blood count variables resulting from consumption of alcohol in Jos North, Plateau State, North Central Nigeria. A total of 281 blood samples were collected by venipuncture from participants, out of which 222 individuals were identified as alcoholics (test group) while 59 were non-alcoholics (control group). Samples were processed in the Department of Medical Laboratory Science, University of Jos. All samples were analyzed using standard laboratory procedures. Data obtained were analyzed using Statistical Package for Social Sciences (SPSS) version 21. The mean values of total protein, albumin, direct bilirubin, total bilirubin, ALT, AST, ALP and GGT for the alcoholics (test) were 63.92 ± 9.23g/L, 31.58 ±4.93g/L, 6.29 ± 2.94umol/L, 16.60 ± 5.93umol/L, 23.09 ± 5.66 U/L, 20.57 ± 6.42 U/L, 251.71 ± 77.72 U/L and 26.26 ± 8.99 U/L respectively, while those of the control groups include 67.72 ± 7.45g/L, 33.96 ± 3.51g/L, 4.67 ± 2.03umol/L, 12.94 ± 4.34umol/L, 12.69 ± 3.29 U/L, 17.28 ± 3.90 U/L, 233.30 ± 65.97 U/L and 24.84 ±7.22 U/L respectively. A weak negative correlation was observed between PCV, eosinophil (r= -0.060; r= -0.081 respectively) and duration of alcoholism. Conversely, a very weak positive association existed between TWBCC, neutrophil, lymphocytes, monocytes (r= 0.081; r=0.001; r=0.018; r=0.0120 respectively) and duration of alcoholism. Regarding duration of alcoholism, we observed both positive and negative linearity of variables with duration of alcohol abuse. In conclusion, this work suggests that alcohol consumption may exert significant changes in some liver and hematological variables.

Keywords: Haematological, Liver, association, alcoholism.


[Full Text Article]

INDEXING

NEWS & UPDATION

  • New Issue Published

    Its Our pleasure to inform you that, EJPMR 1 February 2019 Issue has been Published, Kindly check it on http://www.ejpmr.com/home/current_issues

  • EJPMR FEBRUARY ISSUE PUBLISHED

    FEBRUARY 2019 Issue has been successfully launched on 1 February 2019

  • EJPMR New Impact Factor

    Its our Pleasure to Inform you that EJPMR Impact Factor has been increased from 4.161 to 4.897 due to high quality Publication at International Level

  • Index Copernicus Value

    EJPMR Received Index Copernicus Value 79.57, due to High Quality Publication in EJPMR at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Article are invited for publication in EJPMR Coming Issue

Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (Under Process)