EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (Under Process) , 

 ISSN 2394-3211

Impact Factor: 4.897

 ICV - 79.57

Abstract

EVALUATION OF RED CELL DISTRIBUTION WIDTH IN ANTI-HCV POSITIVE PATIENTS

Nuran Karabulut*, Hakan Ayy?ld?z, Hasan Bayrak5 and Mehmet Kalayc?

ABSTRACT

Objective: Hepatitis C virus (HCV) infection is considered a serious healthcare issue worldwide. Recently, it has been investigated the association between hepatitis B and red cell distribution width (RDW) in the several studies. Elevated RDW levels have been suggested to be a prognostic biomarker for liver diseases. Therefore, it was aimed to investigate the relationship between RDW and anti-HCV in this study. Material and Methods: This retrospective study included 46 anti-HCV positive and 52 anti-HCV negative patients who were analyzed RDW parameters. The anti-HCV positive and negative groups were matched for gender, age, and clinical diagnosis. The anti-HCV test was performed on the Triturus system by ELISA method. RDW parameters were measured on the Mindray BC 3000 Plus instrument by electrical impedance method. Results: White and red blood cell counts, mean corpuscular hemoglobin, mean corpuscular volume, platelet counts parameters between anti-HCV positive and negative groups were no statistically significant. Hemoglobin and mean corpuscular hemoglobin concentration values were higher in the anti-HCV negative group. Red cell distribution width-standard deviation (RDW-SD) values in the anti-HCV positive group were statistically higher than the anti-HCV negative group (50.20 ± 5.37 and 44.72 ± 5.49 fL, p<0.001). Similarly, red cell distribution width-coefficient of variation (RDW-CV) values in anti-HCV positive patients were detected the increased levels compared the patients with the anti-HCV negative. Conclusion: It was detected a significant increase in the RDW values of the patients with anti-HCV positive. RDW parameters which are simple, inexpensive and used commonly in routine, may serve as a significant biomarker for hepatitis C infection.

Keywords: Hepatitis C, HCV, RDW.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (Under Process)