EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (Under Process) , 

 ISSN 2394-3211

Impact Factor: 4.897

 ICV - 79.57

Abstract

ISOLATION AND IDENTIFICATION OF CANDIDA SPECIES WITH THEIR ANTIFUNGAL SUSCEPTIBILITY PROFILE IN A TERTIARY CARE HOSPITAL

Imran Ahamad and Umar Farooq*

ABSTRACT

Introduction: Yeasts are the fourth most common organism recovered from blood culture in hospital. There has been a significant increase in the number of reports of mucosal and systemic Candida infections with non-albicans Candida (NAC) species. Systemic Candida infections are the common to immunocompromised individuals, including human immuno deficiency virus (HIV) infected patients, transplant recipients, chemotherapy patients, and low-birth weight infants.6 Candida species were initially susceptible to azoles group but now some species have developed resistance to the Azoles. Aim: Isolation and identification of candida species with their antifungal susceptibility profile in a tertiary care hospital. Material & Methods: The study was conducted in the Department of Microbiology, Teerthanker Mahaveer Medical college & research centre Moradabad. Candida species isolated from various clinical samples were include in the study. The isolates were identified as per standard mycological protocol. The antifungal susceptibility profile of candida isolates was determined by disc diffusion method. Result: During the study period a total 1156 were processed out of which 100 isolates were taken for Candida. NAC species was predominant isolates. C.tropicalis were the major isolates from NAC species. Highest resistance was seen against fluconazole among both C.albicans and NAC. Conclusion: The present study highlights the predominance of NAC species in ICU patients similar to the trends in various study in our country. The present study highlighted the need for periodic surveillance of antifungal susceptibility pattern to preventing the emergence of drug resistance.

Keywords: Candida species, Non-albicans candida, Immunocompromise Antifungal resistance.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (Under Process)