RELATIONSHIP BETWEEN OBESITY AND ANTI MULLERIAN HORMONE IN WOMEN ABOVE (35) YEARS OLD

Dr. Maysoon Shareif* and Dr. Alyaa Husain Abd

ABSTRACT

Objective: To study the relationship between obesity and anti mullerian hormone as a serum marker of ovarian reserve in women above age 35 years. Methods: This study was conducted in the infertility center in Basrah Maternity and Child Hospital. One hundred women included in the study which were divided into 2 age groups of late pre-menopausal phase; 50 women (obese) (group A) had a Body Mass Index (BMI) more than 30 kg /m2 and the other 50 women (non-obese) (group B) had BMI less than 30 kg /m2. Anti mullerian hormone was measured by ELIZA method. Results: The obese women group(A) had a mean age of (39.9±2.7) years and non obese women group (B) had a mean age of (39±2.7) years. The anti mullerian Hormone level in group A(Obese) was (1.4±0.4) which it was significantly lower as compared to group B (non-Obese) (2.4±0.4) {P<0.01}. Body Mass Index is also negatively correlated with serum anti -mullerian hormone. Conclusion: Obese women have lower anti mullerian hormone levels compared to non obese women in the late reproductive years indicating that obesity is likely to have an affect on ovarian reserve in the pre-menopausal age group.

Keywords: Anti Mullerian, Obesity, Infertility.