EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (Under Process) , 

 ISSN 2394-3211

Impact Factor: 4.897

 ICV - 79.57

Abstract

ACCOMPANYING IMMUNOPHARMACOTHERAPY IN PATIENTS WITH OVARIAN CANCER USING CYCLOFERON AND TACTIVIN

*Kamishov S. V. and Tillyashaykhov M. N.

ABSTRACT

An imbalance in the cytokine: IFN-γ / IL-6 ratios was studied. In norm IFN-γ / IL-6 - 1,2. In the group of patients with OC before treatment: IFN-γ / IL-6 - 0.5; in the group of patients after PCT without the use of immunotherapy - IFN-γ / IL-6 - 0.24; in the group of patients with EIPHT + cycloferon - 1.1, and in the group of patients with EIPHT + tactvin - IFN-γ / IL-6 - 0.9. Thus, in groups of patients with EIPHT and immunotropic drugs, there is a positive trend in the state of the immune system, which is reflected in the immunomodulating effect of IFN-γ and a decrease in IL-6. Apparently the use of immunotherapy in a combination of chemotherapy in our opinion is a justified and effective method that leads to the normalization of immunological parameters of the immune system, improves the immediate results of treatment, leads to a decrease in the intoxication of the disease, leads to a decrease in clinical manifestations of the disease.

Keywords: Cytokines, ovarian cancer, immunopharmacotherapy, polychemotherapy, interferon inducers, thymic preparations.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (Under Process)