EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (Under Process) , 

 ISSN 2394-3211

Impact Factor: 4.897

 ICV - 79.57

Abstract

ANTIBIOTIC PROPHYLAXIS IN CLEAN AND CLEAN-CONTAMINATED SURGERY AND SURGICAL SITE INFECTION IN GENERAL SURGICAL WARDS IN IBRAHIM MALIK HOSPITAL AT KHARTOUM STATE

Israa Yousif Al- Khidir*, Abdalla El khawad, Habab EL Kheir, Sami Galal, Ahmed Abdulla Mohammed Osman, Asim Ahmed Elnour, Ahmed Mohammed Mohammed Nour

ABSTRACT

Background: The use of antimicrobial prophylaxis for surgical procedures is one of the measures employed to prevent the development of surgical site infections. Objectives: To study evaluate the impact of develop antibiotic prophylaxes protocol in clean and clean-contaminated surgery and surgical site infection in general surgical wards in Ibrahim Malik Hospital at Khartoum State. Methods: This is interventional, prospective case-control hospital based study assessed 226 clean or clean contaminated surgical procedures at Ibrahim Malik Hospital for adult patients. A protocol was established by the team consist of clinical pharmacist and two general surgeons. Study populations were divided into two major groups; 113 patients; (case group) underwent surgical procedures and supervised by surgeons who received guidelines for prevention of SSI and (control group) whose surgeons didn’t receive guidelines. Clean Surgical procedures included hernia repair and thyroidectomy, and two clean contaminated procedures (cholecystectomy and appendectomy). Patients’ data was obtained preoperatively and up to 14 days post-operatively through pre-designed questionnaire. Data was analyzed using (SPSS, vers. 23); both frequencies and chi squares were calculated. Results: The SSI was reported with rate of 35.4%; it was significantly less among case group when compared to control group (26.5% vs. 44.2% respectively, P = 0.003). The overall adherence was found significantly higher in case group when compared to control group (56.7% vs. 43.3% respectively, P < 0.0001). Adherence to duration of post-operative antibiotic was reported in 62.8% and 44.2% respectively, (P < 0.0001). Conclusion: The study concluded that, setting protocol for prevention of surgical site infection is significantly effective in reducing the risk of infection.

Keywords: Surgical prophylaxis, surgical site infection, prophylactic antibiotics, wound infection, antibiotics, Sudan.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (Under Process)