EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 4.897

 ICV - 79.57

Abstract

A STUDY OF SLEEP PATTERN IN TYPE 2 DIABETES MELLITUS PATIENTS AND ITS CORRELATION WITH HBA1C

Dr. V. Saravanan and Dr. D. Baby Chitra*

ABSTRACT

Introduction: Sleep disturbances and chronic sleep shortage have turn out to be very common in current society. The quality and quantity of sleep patterns are influenced by cultural social, psychological, environmental, and genetic factors. In recent years, multiple evidence from epidemiological and laboratory research works have shown that disturbed or decreased sleep is linked with glucose intolerance, insulin resistance reduced acute insulin response to glucose and an augmented risk of developing type 2 diabetes . Moreover, decreased or disturbed sleep is associated with cardiovascular disease, decreased quality of life, and economic burden. Because sleep modulates glucose metabolism and homeostasis, and influences quality of life, hence identifying sleep problems may be an important factor in management of type 2 diabetes. However, most studies of sleep and type 2 diabetes have focused mainly on obstructive sleep apnea and restless leg syndromes. There are limited studies on various sleep disturbances among those with type 2 diabetes using polysomnography. We investigated the frequency of undiagnosed sleep disturbances not addressed previously and evaluated the association between sleep disturbances and glucoregulation in group of type 2 diabetic patients using polysomnography and HbA1c. Aim and Objcetives: To investigate the sleep pattern in type2 diabetes mellitus patients and its correlation to their glycemic levels. Materials and Methods: It is a cross sectional study. Thirty patients with type 2 diabetes with age group between 40-60 yrs participated in the study and thirty age matched non diabetic normal subjects were included in control group. After obtaining informed consent persons were subjected to polysomnography and biochemical analysis. Results: The Total Sleep Time (mins) and Sleep efficiency(%) shows a significant decrease in the diabetic patients when compared to the controls. There is a significant decrease in duration of N2& N3 stages of non REM sleep(in mins) along with decrease in REM sleep duration in the diabetic group when compared to the control group. The diabetic group shows a significant increase in sleep latency when compared with the controls. Pearson’s correlation revealed as the duration of diabetes increases there is a decrease in duration and quality of sleep evidenced by decrease in total sleep time and sleep efficiency and increase in sleep latency,also when there is an increase in HbA1c there is a decrease in duration of sleep and sleep efficiency and increase in sleep latency. Conclussion: From this study we can conclude Type 2 diabetes patients have problems in sleep quality .These changes identified in the sleep study could lead to poor glycemic control in type 2 diabetes patients. Type 2 diabetes patients with poor glycemic control should be assessed for sleep disorders and if present it should be corrected to achieve optimum control of blood sugar levels.

Keywords: Sleep, Diabetes mellitus, Polysomnography, HbA1c.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (Under Process)