EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (Under Process) , 

 ISSN 2394-3211

Impact Factor: 4.897

 ICV - 79.57

Abstract

BRAIN RADIONECROSIS IN PATIENTS IRRADIATED FOR NASOPHARYNGEAL CARCINOMA: ABOUT ONE CASE AND REVIEW OF LITARATURE

Taghzout Hasnae*, Chbihi Hassani Ghita, Hafidi Khaoula, Alami Zineb, Bouhafa Touria and Hassouni Khalid

ABSTRACT

Cerebral radionecrosis is a rare, late iatrogenic complication that occurs after more than six months from the start of treatment in irradiated patients for undifferentiated nasopharyngeal carcinoma. This could be explained by the conjunction of vascular, glial and immunological lesions. This may involve the patient's functional and vital prognosis. Conventional MRI (Magnetic resonance imaging), coupled with spectroscopic sequences, greatly contributed to the follow-up of irradiated patients to refine the differential diagnosis between tumor recurrence and radionecrosis. Getting histological evidence by surgical excision or stereotactic biopsy remains to be discussed. given the lack of potentially effective treatment prevention through better dosimetric planning is fundamental. We report a case in a patient treated with induction chemotherapy followed by concomitant radiochemotherapy for locally advanced nasopharyngeal cancers. The diagnosis was guided by spectroscopic MRI and the evolution was favorable under steroids.

Keywords: Cerebral radionecrosis, Nasopharyngeal cancers, radiotherapy, Spectroscopic MRI.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (Under Process)