EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57

Abstract

RA FACTOR AND CRP: MARKERS FOR RHEUMATOID ARTHRITIS

Nitika Sharma*, Dr. Arun Kumar Gupta, Amit Kumar Singh, Mukesh Kumar Singh

ABSTRACT

Rheumatoid arthritis (RA) is chronic disease involving mostly small joints of hand and feet. Antibody – antigen reaction are used for diagnosis. The correct choice and interpretation of these tests depends on detailed knowledge of patients. The aim of our study was to assess serum CRP and RA factor as marker for RA. The study was conducted at department of microbiology, Teerthanker Mahaveer Medical College and Research Centre, Moradabad. In total, 100 patients were included. 88% of samples were positive for CRP and 77% for RA factor. Among 88% patients, 28.4% were male and 71.6% were female whereas in 77% cases of RA, 27.2% were males and 72.8% were female. There was significant association of gender with CRP (p < 0.05).The frequency of positive result was high in age group 41-50 years for both CRP (30.7%) and RA factor (26.1%).The association was found significant between age group and CRP only (p<0.01). When the association between CRP and RA factor was determined, it was found highly significant (p<0.001). RA factor and CRP are the markers used for diagnosis of rheumatoid arthritis. RA factor is more specific and can be detectable in serum only in conditions of Rheumatoid Arthritis.

Keywords: RA (Rheumatoid arthritis), CRP (C- reactive protein), antibody, antigen.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia