EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (Under Process) , 

 ISSN 2394-3211

Impact Factor: 4.897

 ICV - 79.57

Abstract

EFFECT OF METHANOL EXTRACT OF DELONIX REGIA ON FREE RADICAL SCAVENGERS AND LIPID PROFILE OF WISTAR ALBINO RATS

Aloh G.S., Obeagu Emmanue Ifeanyi*, Odo Christian Emeka, Obeagu Getrude Uzoma, Okpara Kingsley Ezechukwu, and Kanu Stella Ngozika

ABSTRACT

Methanol extract of Delonix regia was tried at two doses (250mg and 500mg per kg body weight) for its effect on free radical scavengers and lipid profile of albino rats. Serum levels of superoxide dismutase (SOD) and catalase (CAT) were significantly (P<0.05) lower in the animals that received extract (both doses) than both controls. Also, GSH levels were lower in the animals that received the extract than both controls. However, malondialdehyde (MDA) levels were significantly elevated (P<0.05) in the rats that received the extract when compared with the controls. Vitamins C and E levels did not display dose-dependence and did not differ significantly (P>0.05) from those of the controls. The mean HDL and LDL levels in both groups of rats did not differ significantly (P<0.05) at 250mg but at 500mg, HDL level was significantly lowered and LDL remained constant. Irrespective of dosage, the total cholesterol and triacylglycerol levels of the experimental rats did not differ from those of the controls. The Delonix regia extract displayed mild antioxidant effect and little elevation of HDL and other bad lipids.

Keywords: Delonix regia, malondialdehyde (MDA), mild antioxidant effect.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (Under Process)