EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (Under Process) , 

 ISSN 2394-3211

Impact Factor: 4.897

 ICV - 79.57

Abstract

EFFECT OF ANTIVENOM OF Echis carinatus SNAKE ON HEMATOLOGICAL PARAMETERS AND LIVER ENZYMES OF MALE AND FEMALE RATS

Sami J. Al-Maliki, Khalid G. Al-Fartosi* and Baida R. Ali

ABSTRACT

The present study aimed to investigate the effect antivenom of Echis carinatus on hematological parameters and liver enzymes of rats. Adult male and female rats divided into three groups for each sex (6 for each group), the first group injected (i.p.) with normal saline (0.9%Nacl) as a control group, the second group injected (i.p.) with(0.25ml/kg/day) of antivenom for two times, and the third group injected with (0.5ml/kg/day) of antivenom for two times. Animals killed within 24 hours. Results indicated a significant increase (P≤0.05) in redblood cell count (RBC), meancorpuscular hemoglobin (MCH), mean concentration corpuscular hemoglobin (MCHC) packed cell volume (PCV), mean corpuscular volume (MCV), total (WBC), lymphocytes, monocytes and granulocytes in male and female rats of second andthird groups compared with the control group. Also, it showed a significant increase(P≤0.05) in the number of platelets in third group of male and female rats compared with the first andsecond groups.Also, it showed a significant increase(P≤0.05) in the liver enzymes ALT, AST and ALP in second and third groups of male rats compared with the control group. There was significant increase(P≤0.05) in the liver enzymes ALT, AST in third group compared with the second andcontrolgroup, while showed ALPsignificant increase(P≤0.05) in third compare with the second and control groups.

Keywords: Antivenom, blood parameters, liver enzymes, rats.


[Full Text Article]

INDEXING

NEWS & UPDATION

  • New Issue Published

    Its Our pleasure to inform you that, EJPMR 1 October 2018 Issue has been Published, Kindly check it on http://www.ejpmr.com/home/current_issues

  • EJPMR OCTOBER ISSUE PUBLISHED

    OCTOBER 2018 Issue has been successfully launched on 1 October 2018

  • EJPMR New Impact Factor

    Its our Pleasure to Inform you that EJPMR Impact Factor has been increased from 4.161 to 4.897 due to high quality Publication at International Level

  • Index Copernicus Value

    EJPMR Received Index Copernicus Value 79.57, due to High Quality Publication in EJPMR at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Article are invited for publication in EJPMR Coming Issue

Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (Under Process)