TO STUDY THE CLINICAL PROFILE OF CHILDREN OF TYPE 1 DM, ADMITTED WITH DIABETIC KETOACIDOSIS (DKA) IN PICU.

*Dr. Sudhir Mehta MBBS, DCH, DNB (PEDIATRICS), MRCPCH

ABSTRACT

OBJECTIVE: To study the clinical profile of children of type 1 DM, admitted with diabetic ketoacidosis (DKA) in PICU. METHODS: We retrospectively analysed the case records of 40 children admitted with DKA to our intensive care unit, from 2010-2015. Information regarding personal details, chief complaints, clinical features, laboratory parameters, management and outcome was recorded using a predesigned proforma. RESULTS: The median age at presentation was 9 years (range 3 yr- 16yrs); 17 boys and 23 girls were enrolled. Diabetes was newly diagnosed in 25 cases and known cases of type1 diabetes were 15. Commonest presenting complaints were febrile illness (76%), rapid breathing (62%), vomiting (61%), and altered sensorium (24%). Average length of PICU stay was 72 hrs. All of the cases had elevated HbA1c, except two. Co-morbities found was UTI in 15 (37%), and Cerebral edema was seen in 5 cases. There was no mortality in our study. CONCLUSION: DKA in children if diagnosed early and managed timely has good outcome. Poor compliance is most important precipitating factor in known cases of T1DM.

Keywords: Diabetic Ketoacidosis, Type I DM, Cerebral Edema.