EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (Under Process) , 

 ISSN 2394-3211

Impact Factor: 4.897

 ICV - 79.57

Abstract

EVALUATION OF GLOMERULAR FUNCTION IN WOMEN WITH PREECLAMPSIA.

Dr. Amit D. Sonagra.*, Dr. Asmabi Makandar, Dr. Shrikant Chandrakar, Dr. Juhi A. Sonagra and Dr. K. Dattatreya

ABSTRACT

Introduction: Preeclampsia is defined as elevation of BP ≥140/90 mm of Hg after 20 weeks of gestation and proteinuria of ≥300mg/24hours or ≥1+ by dipstick method in a random urine sample. Preeclampsia causes widespread endothelial dysfunction leading to hypertension. It is associated with high occurrence of damage to kidney glomeruli. Damage to kidney may lead to elevated serum creatinine levels & reduced Glomerular Filtration Rate (GFR) which can be used for evaluation of glomerular function. Objectives: To compare and to evaluate role of serum creatinine level & GFR among women with preeclampsia & normal pregnancy. Materials and methods: Case control study was done taking 35 women with preeclampsia as cases and 35 women with normal pregnancy as controls. Serum creatinine was measured using Jaffe’s Kinetic method. GFR was calculated using Cockcroft-Gault formula & MDRD formula. Statistical analysis was done using SPSS 17.0. Results: Serum creatinine was significantly increased in cases when compared with controls (p<0.001). GFR was significantly low in cases when compared with controls (p<0.001). Conclusions: Presence of glomerular damage leads to elevated serum creatinine & reduced GFR. GFR gradually decreases as the disease severity increases. Regular monitoring of GFR in women with preeclampsia may give a clue of associated kidney damage.

Keywords: Cockcroft-Gault formula, glomerular filtratition rate, MDRD formula, preeclampsia, serum creatinine.


[Full Text Article]

INDEXING

NEWS & UPDATION

  • New Issue Published

    Its Our pleasure to inform you that, EJPMR 1 March 2019 Issue has been Published, Kindly check it on http://www.ejpmr.com/home/current_issues

  • EJPMR MARCH ISSUE PUBLISHED

    MARCH 2019 Issue has been successfully launched on 1 March 2019

  • EJPMR New Impact Factor

    Its our Pleasure to Inform you that EJPMR Impact Factor has been increased from 4.161 to 4.897 due to high quality Publication at International Level

  • Index Copernicus Value

    EJPMR Received Index Copernicus Value 79.57, due to High Quality Publication in EJPMR at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Article are invited for publication in EJPMR Coming Issue

Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (Under Process)