FREQUENCY, PREFERENCES AND PRESCRIBING PATTERN OF ANTIMICROBIALS IN OUTPATIENT DEPARTMENT OF A TERTIARY CARE SGM HOSPITAL AT CENTRAL INDIA, REWA MADHYA PRADESH.

*Singh Prabhakar, Shrivatava Roshani, Singh Amita, Shrivatava A.K., Raj Bhupendra and Ambika V.J.

ABSTRACT

Aims and Objectives: The aim of study is to determine the prescribing pattern and utilization trend of antimicrobials in a tertiary care hospital. Material and methods: Study was conducted in the department of Pharmacology SS Medical College and SGM. Hospital, Rewa, MP, from September 2013 to June 2014. The prescriptions were collected randomly, after taking the consent from patients who attending outpatient department of SGM Hospital. The prescription slips were taken in form of Xerox copy and analyzed. Results: The result of study showed that most of the prescriptions (43.57%) were belongs to 33-42yrs of age group with their mean age (±SD) 37.78 ± 13.36 yrs, of these 59.25% were females. Amongst the antimicrobials, fluoroquinolones were the most frequently prescribed group (25.10%) followed penicillin (18.31%), fixed dose combination of ciprofloxacin plus tinidazole (14.57%) and amoxicillin plus cloxacillin (8.40%), anti-amoebics (7.38%), tetracycline (6.59%). The total 3047AMAs were prescribed in 3587 prescriptions; the average number of drugs and AMAs per prescriptions is 2.27 and 0.82 respectively. 98% of AMAs were prescribed from essential medicine list of India and 100% from EML of WHO. In these AMAs, 88.05% were prescribed by generic and 11.94% by brand names. Conclusions: Rational prescription of antibiotic is very important to prevent antimicrobial resistance. In this study fluoroquinolones is the most frequently prescribed group which is principally act on gram negative bacteria, especially enterobacteriaceae; hence it is necessary to make formulation policy for hospital antibiotic use and an educational programme especially for prescribing doctors.

Keywords: Prescriptions; Outpatient Department (OPD); Antimicrobials; Polypharmacy.