ANTIMICROBIAL SCREENING AND ANTIOXIDANT POTENTIAL OF MENTHA PIPERITA OF DODDABALLAPUR TALUK, BENGALURU RURAL DISTRICT KARNATAKA

Dr. Rajeev Ramachandra Kolgi*, Bindu C. A., Aravinda T. S., Gayithri V., Likhitha K. V., Shilpashree S.

ABSTRACT

Leaves of plant extract from Mentha piperita (commonly known as mint) are studied for its therapeutic activity. The sample (Mint extract) was tested in duplicates for their MIC property against organisms Pseudomonas aeruginosa, Salmonella typhi, Staphylococcus aureus and Streptococcus mutans, the crude ethanol leaf extracts showed significant antibacterial activity. The antioxidant property was conducted by invitro method of 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay was conducted on the crude leaves ethanolic extract. DPPH assay showed 49% radical scavenging activity at 500 μg/ml. The antioxidant activity of the samples was compared to the gallicacid as a standard. This study revealed that the ethanolic extract of the plant is good source of antioxidants. It could explain and justify some of their uses in traditional medicine and they need further exploration for their use in modern system of medicines.

Keywords: Mentha piperita, gallic acid, DPPH radical scavenging, MIC.