THE STUDY OF VYASAN (ADDICTION) HETU FOR PATHOGENESIS W. S.R TO ORAL SUBMUCOSAL FIBROSIS

*Dr. Nitesh S. Deotale and Dr. Ujwala V Pawar

ABSTRACT

Lifestyle disorder primarily based on daily habits, Some common disease are ,Alzheimer disease, cancer, arteriosclerosis, cirrhosis, COPD, DM,HTN, etc. They take year to develop caused by factor heat, sound, dust, fumes, smoke. Vyadhi occurred by doshdushti and dhatudourbalya, etiological factor are ahara, vihara, vyasana, manas&aushadhi. Vyasan are of different kinds like alcohol, tobacco pan- guthakha, smoking etc. gutakha and pan masala are widely used because of low cost, easily available, easily handle. On routine observation seen that these vyasan cause OSF. According to ayurveda nidan, doshdushti, dhatudushti, dhatuvikruti (Twak), reversible and irreversible. In OSF it is reversible, cause by vata kapha, 70% of oral cancer are vata kapha, according to modern arecoline(alkaloid) stimulate fibroblast and increase production of collagen by 150%. Oral sub mucous fibrosis is a chronic disease of the oral sub mucosa characterized by inflammation and progressive fibrosis, which has high risk of malignant transformation. It can be prevented by changing lifestyle and sesation of chewing betel nut. The fibrosis can be reversible, By the use of Bhallataka which is anticancerous drug and also vatakaphaghna may be effective in OSF.

Keywords: According to ayurveda nidan, doshdushti, dhatudushti, dhatuvikruti (Twak), reversible, irreversible.