A PROSPECTIVE CROSS-SECTIONAL STUDY TO ASSESS THE ETIOLOGICAL PROFILE, PATIENT KNOWLEDGE AND DRUG UTILIZATION PATTERN AMONG CHRONIC KIDNEY DISEASE PATIENTS IN A TERTIARY CARE HOSPITAL

Shamna Haris*, Sandeep Sarma S. S., Rittu R. L., Deepa Manohar and Dr. Bincy Babu

ABSTRACT

Background: Chronic kidney disease is a condition characterized by gradual loss of kidney function over time which leads to a reduction in the glomerular filtration rate (GFR) accompanied by proteinuria. Evaluation of patient knowledge in CKD patients help to assess the degree of knowledge level regarding disease condition and assessment of drug utilization pattern helps to evaluate the various drugs used for the management of CKD and its complications. The aim of the study was to assess the etiological profile, patient knowledge and drug utilization pattern among chronic kidney disease patients. Methodology: This is a prospective cross-sectional study carried out among CKD inpatients in Tertiary Care Hospital, Trivandrum for a period of 6 months. A total of 110 patients were included in the study. Results: A total of 110 patients were analyzed during the study, of which 70% were males and 30% were females. CKD was found to mostly affect the age group of 41-60 (43.63%). Most common etiology of CKD were Hypertension (85.45%) and Type II DM (81.81%). Most common complications were anemia (86.36%) and metabolic acidosis (63.63%). Antihypertensive and diuretics were the most commonly prescribed drugs. Majority of the population were found to have an average level of knowledge (49.09%). Conclusion: The study demonstrated that hypertension was the major etiology and Anemia was the major complication in study population. Antihypertensive and diuretics were the most commonly prescribed drugs. Majority of the population had an average level of knowledge and moderate adherence. Analyzing the pattern of drug use and improving the knowledge and adherence helps to improve the therapeutic outcome.

Keywords: CKD, Drug utilization pattern, Patient knowledge, Drug related problems.