ORGANO-SULFUR COMPOUNDS OF GARLIC OIL: PROMISING THERAPEUTIC POTENTIAL

Rimpa Malakar, Brahmarshi Das, Bidyut Kumar Khuntdar, Rumi Mahata and Sujata Maiti Choudhury*

ABSTRACT

Garlic (Allium sativum) is a plant of the family Allium and it has been using as a potential medicinal herb for prevention and treatment of inflammation, gastro-intestinal disorders, microbial infections, hypertension and many other health disorders. This review is aimed to highlight the therapeutic effects of different organosulfur compounds (OSCs) derived from Allium sativum. OSCs of garlic oil are allicin and its derivatives like allyl sulfide, diallyl disulfide, diallyl trisulfide, E-ajoene, Z-ajoene, etc. The phyto-chemicals derived from Allium sativum possess therapeutic health benefits such as, anti-diabetic, anti-inflammatory, anti-bacterial, anti-fungal, anti-viral, protective role against cardiovascular diseases, hypotensive, hypo-cholesterolemic even anti-tumor, anticancer, and antimetastatic without contributing any harmful side effect.

Keywords: Garlic, Organo-sulfur compounds, Phyto-medicine, Therapeutic uses.