THE ROLE OF THE IMMUNE SYSTEM IN THE FORMATION OF ENDOTHELIAL DYSFUNCTION IN CASE OF VIOLATION OF THE UTEROPLACENTAL BLOOD CIRCULATION

Musakhodjaeva Diloram A.*, Fayzullaeva Nigora Ya., Yeshimbetova Gulsara Z., Jum??v? Dildora M., Sadykova ?h??if? Z., ?uzaf?r?v? Salima A., An Andrey V., Azizova Zukhra Sh, Rustamova Nazokat B. and Ruzimurodov Nodirjon F.

ABSTRACT

Background: This article considers the value of uterine-placental circulation in the process of growth and development of the fetus during pregnancy. The mechanisms of the formation of epithelial dysfunction in case of violation of the uterine-placental and surgery are considered and the significance of immunological and endothelial biomarkers is reflected. Violations of the uterine-placental blood flow leads to such complications of pregnancy as preeclampsia, fetal growth, hypoxia up to death. The regulation of the uteroplacental circulation is vital for the well -being of the mother and fetus.

Keywords: Endothelial Dysfunction, Endothelium, Fetal Growth Retardation, Uteroplacental Blood Flow, Immunity.