COMPARATIVE HEAVY METAL ANALYSIS AND MICROBIAL OVERLOAD STUDY OF SANJIVANI VATI PREPARED FROM TWO DIFFERENT MEDIA FOR SHODHANA OF VATSANABHA

*Dr. Meenu Bharti Sharma, Prof. Dr. Upendra U. Zala and Dr. Ankit M. Paneliya

ABSTRACT

Introduction: Sanjivani Vati is polyherbal formulation. It has two Visha present into it which are Vatsanabha and Bhallataka. Ashuddha Vatsanabha (Aconitum Chasmanthum Stapf Ex Holmes) is very toxic in nature. For therapeutic use, Vatsanabha can be use after Shodhana only. In this study, two different kind of media (Gomutra & Godugdha) were taken to purify Ashuddha Vatsanabha. And after that two different batches of Sanjivani Vati (SVA- by using Godugdha Shodhita Vatsanabha Powder and SVB- by using Gomutra Shodhita Vatsanabha Powder) were prepared. Now, to see any changes after Shodhana as well as comparison of two media were done. For that, we have compare the Heavy metal analysis and Microbial Overload to know the presence and comparison between both batches of Sanjivani Vati. Material and Methods: Principle of Heavy metal analysis & Microbial Overload, Instruments and steps involved in procedure using specify techniques. Results and observation- Both the samples were observed and resulted into the range of standard limits. Discussion- Both the samples SVA & SVB, in table 1 and table 2 showed the permissible and acceptable limit which indicates safety aspect. Conclusion- Both the Samples of Sanjivani Vati showed the value in permissible limit in Heavy metal analysis and acceptable range of microbial overload. In comparison, to both the samples SVA sample prepared by using Godugdha media showed more less value in both parameters than Gomutra media. But the range value of both samples for the study indicates the safety and acceptability for further use.

Keywords: In this study, two different kind of media (Gomutra & Godugdha) were taken to purify Ashuddha Vatsanabha.