SURGICAL SITE INFECTIONS AMONG PATIENTS UNDERWENT CRANIOTOMY IN KHOULA HOSPITAL: RATE, RISK FACTORS, MICROBIOLOGY FEATURES, CLINICAL OUTCOME ( 2009- 2019).

Dr. Ayesha Al Balushi, Amal Al Jabri, Neeraj Salhotra*, Samit Biniwale, Ahmed Wadee and Arshi Arif

ABSTRACT

Objective: To assess the overall clinical outcome of SSI post craniotomy in Khoula hospital in Oman between 2009-2019. Also, it provides data regarding the rate, risk factors and microbiology features of SSI post craniotomy in Oman. Method: A retrospective descriptive cohort study conducted in Khoula hospital, include all adult craniotomy cases between 2009-2019. Data collected from Al Shifa system using Excel sheet. All SSI are identified by National Healthcare Safety Network (NHSN) and categorized according to Centre of Disease of Prevention (CDC). Data is analyzed by SPSS program version 24. Result: Of the 547 patients undergoing craniotomy during the study period, 35 developed SSI. Among the 35 patients who developed SSI. The most frequent causative Gram-positive organisms were Coagulase Negative Staphylococci11.4%), whereas Pseudomonas aeruginosa (8.5%) was the most commonly isolated Gram- negative agent. In the univariate analysis the factors associated with SSI-CRAN were clean-contaminated surgical site (p =0.006), Use of steroid/chemotherapy pre-operation 2 weeks (p =0.023), and presence of implant (p = 0.020). In the multivariate analysis, Clean-Contaminated surgical site and presence of implant were the only factors independently associated with SSI-CRAN. In summary, The risk factors and causative agents of SSI-CRAN identified in this study should be considered in the design of preventive strategies aimed to reduce the incidence of this serious complication.

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