NON-STEROIDAL ANTI-INFLAMMATORY DRUGS INDUCED ACUTE KIDNEY INJURY- A CASE REPORT

Aparna Matpathi*, Shagupta Shalu, Ramya Balaprabha G., Ramarao Tadikonda

ABSTRACT

NSAIDs are widely used drugs and are generally safe, but their usage should be limited to avoid causing damage to the kidney's structure and potential renal impairment. This case study includes a woman with history of NSAID abuse to alleviate knee pain. She developed AKI due to excessive usage of NSAID. She had hypoalbuminemia, increased ESR, increased serum creatinine levels and increased ESR, decreased GFR and reduced urine output which play a key role in diagnosing AKI along with thorough physical examination. The role of loop diuretics like furosemide to rule out edema and to improve AKI has been discussed. Appropriate treatment strategies to overcome other than performing dialysis, as dialysis shows promising results, but it has its own challenges that need to be overcome.

Keywords: Non-steroidal anti-inflammatory drugs, Acute kidney injury, Serum creatinine levels, Glomerular filtration rate, Furosemide, Antibiotics, Anti-inflammatory medications.