A REVIEW ON BIOLOGICAL ACTIVITY OF BENZOTHIAZOLE DERIVATIVES

Swaroopa H. M., Sandhya M., Manoj A. Sharon*, Nagesh T. and Shahabas

ABSTRACT

Benzothiazole is a bicyclic heterocycle having thiazole ring and are used worldwide for a variety of therapeutic applications. The core structure of thiazole consists of a five-membered ring containing sulfur and nitrogen atom at 1st and 3rd positions. Benzothiazole and their derivatives represent an important class of compounds possessing a wide spectrum of biological activities. The several analogues containing benzothiazole ring system exhibit significant antitumor, anthelmintic, antitubercular, antimicrobial, antidiabetic, antibacterial, antifungal, antioxidant, anti-inflammatory and other activities. This article is an attempt to present recent scientific literature on different biological activities of benzothiazole compounds.

Keywords: Benzothiazole, Antitumor, Anthelmintic, Antimicrobial, Antioxidant, Antifungal.