EVALUATION OF SERUM LIPID PROFILE IN POSTMENOPAUSAL WOMEN

Sumayra Jhumu*, Humayra Rumu, Rumana Ferdous, Mohammad Rashedul Islam Akand, Md. Mamunur Rahman and Sarmin Sultana

ABSTRACT

Background: The serum lipid profile of postmenopausal women often undergoes notable changes due to the hormonal shifts that occur during and after menopause. These changes can have implications for cardiovascular health and overall well-being. Objective: To assess serum lipid profile in postmenopausal women. Methodology: This cross-sectional descriptive study was carried out at Department of Physiology of Rajshahi Medical College from July 2018 to June 2019. Where 200 healthy postmenopausal women aged 50-70 years in Rajshahi city were included as sample size. The healthy adults who were fulfill the inclusion criteria was enrolled in this study. After taking informed consent, complete history taking and physical examination was done and recorded in a preformed data sheet. Results: 80% of postmenopausal women have abnormal serum triglyceride level and 20% of postmenopausal women have normal serum triglyceride level out of 200 postmenopausal women. 95.5% of postmenopausal women have low serum HDL-C level (<50 mg/dl) and 4.5% of postmenopausal women have normal serum HDL-C level (>50mg/dl). 11.0% of postmenopausal women have abnormal serum LDL-C level and 89.0% of postmenopausal women have normal serum LDL-C level out of 200 postmenopausal women. The mean serum total cholesterol level in group- I of postmenopausal women were 194.14±37.49 mg/dl and group- II of postmenopausal women were 195.10±31.41 mg/dl, which does not differ significantly. Conclusion: Increased LDL-C level (11%), increased total cholesterol level (9.5%), low HDL-C level (95.5%) in postmenopausal women. TG level were increasing with age of postmenopausal women and it was statistically significant. LDL-C, total cholesterol, HDL-C level does not differ significantly among different age groups of postmenopausal women. There was mixed type of hyperlipidemia was present in postmenopausal women.

Keywords: Serum lipid profile, serum LDL, postmenopausal women.