INFLAMMATORY BOWEL DISEASE: AN OBSERVATIONAL STUDY ON RISK FACTORS AND MEDICATION MANAGEMENT

Dr. Nuzhath Irfana*, Ayesha Wajid, Mohd Shoaib and Sumayya Sultana

ABSTRACT

Inflammatory Bowel Disease (Ibd): Inflammatory bowel disease (IBD) is a term used to describe a range of idiopathic chronic inflammatory bowel diseases. Crohn's disease (CD) and ulcerative colitis (UC) are the two main disease groups, with both overlapping and unique clinical and pathological features.[1] Methods: 20 patients were enrolled in the study, which includes all Inpatients and Outpatients diagnosed with IBD, this study was done to have better understanding of disease. Data from patients was gathered. All information relevant to the study were collected at the time of admission till the date of review follow up and thedata was analysed after entering into Microsoft excel sheet and frequency tables was calculated using suitable method for statistical analysis. This Study was conducted at care hospital and the references were identified with related article searches. Results: Our study results show the possible risk factors associated with the disease. Of the 20 cases, the average age group of those affected was 30–40 years old, with females being more susceptible. The patients were separated into groups based on their risk factors: 10% were smokers, 10% were alcoholics, 30% were obese, 50% were idiopathic, and 20% were using oral contraceptives. In our study, oral mesalamine was provided to 7 patients (35%), topical mesalamine (enema) to 3 patients (15%), and steroids with infliximab to 2(15%)to reduce inflammation and for mucosal healing. Conclusion: IBD is chronic remitting and relapsing disease with mostly idiopathic etiology. Our study results show the possible risk factors associated with the disease and support the hypothesis of an increased risk of inflammatory bowel disease due to obesity. We also found that smoking, alcohol consumption and oral contraceptives have a deleterious impact on inflammatory bowel illness. Medication management is mostly by mesalamine (oral and topical), steroids and antibiotics with supportive management.

Keywords: .