PULMONARY ASPERGILLUS OVERLAP SYNDROME-ALLERGIC BRONCHO PULMONARY ASPERGILLOSIS WITH ASPERGILLOMA

Riya Varghese*, Rona Mariam Chacko, Dr. Luke Mathew, Dr. Stephen Sunny

ABSTRACT

Aspergillus overlap syndromes refer to the occurrence of multiple forms of Aspergillus-related diseases within a single individual. These diseases are caused by various species of the Aspergillus fungus. The main categories of pulmonary aspergillosis include chronic forms of aspergillosis, allergic bronchopulmonary aspergillosis (ABPA), and invasive aspergillosis. Overlap syndromes can occur when an individual has a combination of these forms of aspergillosis or experiences transitions between them. For example, a person with asthma may develop ABPA and later progress to chronic forms like CPA if not appropriately treated or managed. Effective management and treatment require a thorough understanding of the specific forms of aspergillosis the individual is experiencing and tailored medical interventions to address their unique situation. We present the case of a 61-year-old gentleman, who developed ABPA with aspergillosis. We assessed the cause and it was found that he had pulmonary tuberculosis in the past.

Keywords: Pulmonary Aspergillus overlap syndrome; Allergic bronchopulmonary aspergillosis; Smear Positive Pulmonary Tuberculosis; Relapse.