A REVIEW ON PHYTOSOMES: A POTENTIAL NANOCARRIER FOR EMERGING DRUG DELIVERY OF PHYTOCONSTITUENTS

Bhavin D. Pandya* and Ajay K. Saluja

ABSTRACT

The phytoconstituents extracted from plants show poor solubility and poor in-vivo absorption which greatly limits the widespread applications of the herbal active constituents. A phytosomes shows potential nanocarrier for emerging drug delivery of phytoconstituents by incorporation of phyto-phospholipid complexes to increase the in-vivo bioavailability of herbal active constituents, which contains phospholipids and phyto constituents. Hydrogen bond interactions between phyto constituents and phospholipids can be formulated as phytosomes. In this review, structure, properties, advantages, disadvantages, types, methods for preparation, characterization, therapeutic applications, marketed preparations of phytosomes are included.

Keywords: Phytosomes, Phytoconstituents, Bioavailability.