EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

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An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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Abstract

INVESTIGATION OF ANTIBACTERIAL ACTIVITY OF SALACIA RETICULATA (ROOT) AGAINST SOME IMPORTANT PATHOGENIC BACTERIA

Dr. Harishekar M. B., Dr. Kiran B.* and Dr. Lalitha V.

ABSTRACT

Different solvent extract viz., petroleum ether , chloroform , methanol and ethanol extracts of root of S. reticulate was evaluated for antifungal activity against four different bacterial species viz., Staphylococcus aureus , Escherichia coli, Bacillus subtilis and Pseudomonas sp. among the four solvent extract tested, petroleum ether extract recorded a maximum inhibition against all the test bacteria tested at 500, 1000, 1500 and 2000 ppm concentration and compared to synthetic antibiotic chloramphenicol tested at 25mg concentration. Petroleum ether extract was subjected for TLC and the three fractions (each fraction consists of three bands) was identified and among three fractions, fraction II (with Rf value of the band 0.30, 0.33 and 0.36) recorded a maximum inhibition against all the test bacterium.

Keywords: S. reticulate, antibacterial activity, fractions, bioactive principles.


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SJIF Impact Factor: 7.065

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