THE CURRENT STATE OF THE ISSUE OF THE PREVALENCE AND MOLECULAR DIAGNOSIS OF THE RESPIRATORY ALLERGY SPECTRUM BASED ON MULTIPLEX ANALYSIS (REVIEW)

*Iskandarov Sh. T., Ismailova A. A. and Dzhambekova G. S.

ABSTRACT

The aim of the study is to analyze the features of the spread and modern molecular diagnostics of respiratory allergic diseases (AD). Results and Discussion: Allergic deseases are among the most common in children, and in recent years there has been a significant increase in frequency, the formation of a more severe progressive course, the presence of combined manifestations with damage to several organs, are considered as a major medical and social problem of modern society. The development of molecular allergology, including the development of recombinant allergens, for accurate diagnosis and effective allergovaccination by allergen-specific immunotherapy (ASIT) is one of the most promising areas in allergology. Conclusion: Molecular allergodiagnostics is a diagnosis using recombinant allergens. A recombinant allergen is a purified, cloned, and sequenced allergen source. It is important to use innovative technologies for the diagnosis of patients with allergic diseases using a solid-phase immuno-allergochip, the ImmunoCAP ISAC method.

Keywords: allergic diseases, respiratory allergy, molecular allergy, bronchial asthma, allergic rhinitis.