PHARMACOLOGICAL ACTIVITY OF Selaginella doederleinii Hieron: AN UPDATED REVIEW

Putri Zulkarnaen, Nurul Fadila, Laila Nurul Fadhilah, Kartika, Khintan Kardila, Nadila Laely, Najwa Rihhadatul Aisy, Fitria Wulandari, Amanda Imaniar Khoirunnisa, Maulidiah, Safitri Hidayatus Salamah, Sri Saofi Febri Tri Syifa, Agnia Rizki Wahdah, Ridwan Hidayat, Ghifari Hanif Hermawan and Maulana Yusuf Alkandahri*

ABSTRACT

Selaginella doederleinii, a medicinal herb of general recognition that is a member of Selaginellaceae family, is prevalent in Guangxi province, China. It is alternatively referred to as immortality grass. Presently, an abundance of research established that S. doederleinii possesses medicinal properties and is capable of a wide range of pharmacological actions. Parts of this plant are documented to possess diverse pharmacological activities in traditional medicine, with particular emphasis on the leaves, roots, and twigs. These components are utilized for their antiviral, anti-inflammatory, anticancer, antioxidant, antihyperuricemia, antibacterial, antihypertensive, and potential therapeutic properties in the treatment of alzheimer's disease. The primary constituents of this botanical specimen comprise phytone, cedrol, 2-pentylfuran, caryophyllene, and n-hexadecane. Anthraquinone, chamomile, adenosine, biapigenin, adenosine, benzoate ester, β-caryophyllene, and zingerone are additional constituents.

Keywords: Selaginella doederleinii, Medicinal plants, Antiviral, Anti-inflammatory, Anticancer, Antioxidant, Antihyperuricemia, Antibacterial, Antihypertensive, Alzheimer's disease.