PREPARATION AND ANTIMICROBIAL STUDY OF RASAKARPOOR MALHAR (IN-VITRO)

Manasi Nandlal Maurya* and Sheela Pargunde

ABSTRACT

Rasakarpoor is a Nirgandhak Kalpana of Parad mentioned in Rasataragini, which holds antimicrobial activity and is effective in Dushta Vrana (non-healing wounds/NHW). In combination of Rasakarpoor Malhar Sneha, Ghritam and Madhu plays role of healing agent and act as antimicrobial ointment used for external application. Pre-Clinical evaluation of this drug has been done to check its efficacy on Dushta Vrana, its cidal and static activity on micro-organism and to know the duration/time taken by Malhar to heal the wound of specific region. While developing this formulation analytical parameters necessary for Malhar Kalpana were taken into consideration to maintain the quality of the drug. Rasakarpoor is a preparation that achieves modern parameters required for a formulation to sustain to prove its quality and safety. Rasakarpoor holds antimicrobial properties against gram positive and gram-negative bacteria and was proven with invitro study.

Keywords: Rasakarpoor, Malhar, Antimicrobial, Dushta Vrana, Non-Healing Wound.