EVALUATION OF ANTI-HYPERLIPIDEMIC POTENTIAL OF SYZYGIUM CUMINI & HELIANTHUS ANNUUS SEEDS IN THE SUITABLE EXPERIMENTAL ANIMAL MODEL

Aadil Saifi*, Nasiruddin Ahmad Farooqui and Shamim Ahmad

ABSTRACT

This research highlights the potential of medicinal herbs like Helianthus annus and Syzygium cumini to reduce cholesterol levels in the body, which might be important in preventing cardiovascular issues such as atherosclerosis. Significantly, when these herbs were administered at a dose of 0.75 + 0.75 ml/kg, there was a significant decrease in cholesterol levels. Nevertheless, more inquiries are necessary to thoroughly examine the whole range of advantages obtained from these oils extracted from seeds. Polyphenols, which are recognized for their ability to prevent oxidation, may possibly hinder the oxidation of LDL cholesterol, thus leading to the observed reduction in lipid levels. Despite the lack of a clear understanding of the exact mechanism, it is important to further investigate the beneficial effects of polyphenols. This highlights the need for more scientific investigation to clarify the underlying processes. The blend of these botanical extracts produced encouraging hypolipidemic outcomes, as shown by its impact on cholesterol levels in a Triton-induced rat model. Certain results provide a fundamental comprehension of the possible curative advantages of certain botanical extracts, setting the basis for future investigations in this field.

Keywords: This highlights the need for more scientific investigation to clarify the underlying processes.