EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia ,

ISSN 2394-3211

Impact Factor: 7.065

ICV - 79.57

Abstract

SOLID LIPID NANOPARTICLES AS ATTRACTIVE DRUG CARRIER: COMPOSITION, PREPARATION AND APPLICATION

Arathi T. P.*, Shripathy D. and A. R. Shabaraya

ABSTRACT

Solid lipid nanoparticle (SLN) introduced in 1991, have emerged as an alternative to traditional colloidal carriers like liposomes, polymeric nanoparticles, microparticles, and emulsions. SLNs show various distinctive features such as low toxicity, large surface area, prolonged drug release, targeted drug delivery, superior cellular uptake as compared to traditional colloidal carriers as well as capability to improve solubility and bioavailability of drugs. This paper gives an overview about the potential advantages and also the disadvantages of solid lipid nanoparticles, the excipients, classification of SLN, all the different methods involved in their production and biomedical application.

Keywords: solid lipid nanoparticle, colloidal carriers, targeted drug delivery.

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