EXPLORING THE BIOACTIVE COMPOUNDS OF ACALYPHA INDICA THROUGH GAS CHROMATOGRAPHY-MASS SPECTROMETRY: SHEDDING LIGHT ON ITS MEDICINAL POTENTIAL
Dr. Sethuramani A.*, Sasikumar A., Raxshiya Smily J., Chandrasamy M., Dr. Venkata Rathina Kumar T., Dr. Abdul Hassan Sathali A.
ABSTRACT
Copper leaf, scientifically known as Acalypha indica, a member of the Euphorbiaceae family, has long been used in Indian medicine, particularly in Ayurveda. This herb exhibits antiinflammation, analgesic, antipyretic, and antispasmodic properties. Historical uses of Acalypha indica include treating fever, inflammation, pain, and gastrointestinal conditions. As a traditional healing method, its leaves are crushed and applied topically to wounds to reduce inflammation and prevent infection. Furthermore, it regulates menstrual cycles and relieves menstrual cramps. GC-MS analysis of ethanolic extracts of Acalypha indica leaves was performed in the present study in order to identify bioactive compounds. Several different compounds were found in the substance, including phenols, terpenoids, alkaloids, carboxylic acids, aromatics, nitro compounds, and esters. In general, terpenoids, fatty acids, and phenols were found to be the most prevalent compound classes, followed by other cyclic compounds. There was a higher retention time for DL-alpha-tocopherol (37.8324), Cholesterol (37.6496), Gamma tocopherol (36.6378) and Lupeol (35.2932). The extract also contains triterpenoids, such as beta-amyrin, obtisifolid, and lupeol, which may be beneficial for the management of migraines. In addition to providing significant implications for holistic wellness across a wide range of health domains, Acalypha indica demonstrates its versatility as a herbal remedy.
Keywords: GC-MS bioactive compounds, Acalypha indica, Terpenoids, Cyclic compounds, Herbal remedy, Traditional medicines.
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