CASE REPORT: SORAFENIB INDUCED CUTANEOUS EROSIONS: A RARE SIDE EFFECT
Dr. Aakanksha, Dr. Nita Kumari, Dr. Upasana Chauhan*
ABSTRACT
Adverse skin reactions occur in 90% of patients treated with angiogenesis inhibitors. In some cases, a correlation has been observed between the severity of reactions and treatment efficacy and tumour response. Sorafenib is an orally active multi-kinase inhibitor which blocks both tumour cell proliferation and angiogenesis. The most common treatment-related cutaneous adverse effects are rash/desquamation (66%), alopecia (53%), stomatitis/ pharyngitis (35%), dry skin (23%) and flushing (16%). The following case report focusses on a less reported side effect of the drug: cutaneous erosions.
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