THE RELATIONSHIP BETWEEN ENTAMOEBA HISTOLYTICA AND COLON CANCER

Najlaa Turki Munawer*

ABSTRACT

Entamoeba histolytica infections are prevalent in the gastrointestinal tract, particularly in developing regions. While colonic amoebiasis with colon carcinoma is rare, study where Entamoeba trophozoites coexisted with colon cancer. The trophozoites were identified using Periodic acid Schiff (PAS) stain, highlighting their presence. patients received metronidazole treatment, and two underwent subsequent resection followed by adjuvant chemoradiotherapy. Detecting this coinfection is crucial due to the immunocompromised state of cancer patients, many of whom undergo adjuvant chemotherapy and radiotherapy. Neglecting Entamoeba coinfection in such cases could lead to severe complications like dissemination to the brain, liver, lungs, and pericardium. This series underscores the importance of considering parasitic coinfections in colon cancer cases, especially in endemic areas.

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