STUDY ON GREEN SYNTHESIS OF COPPER NANOPARTICLES BY USING DIFFERENT PLANT EXTRACTS & ITS CHARACTERIZATION, ANTIMICROBIAL AND ANTIOXIDANT STUDIES

V. Asha Ranjani*, G. Tulja Rani, M. Gowthami, M. Harika and P. Tharun

ABSTRACT

The report presents a cost-effective method for synthesizing Copper nanoparticles (Cu NPs) using various plant extracts. The NPs have a size range of 5-20 nm and show antibacterial activity against gram-positive and gram-negative microorganisms. The study suggests that green synthesis of metallic nanoparticles could be an alternative to hazardous compounds and bitter reaction conditions. The NPs' unique structural properties and biological effects make them suitable for applications like antimicrobial, antifungal, and anticancer activity. The study investigates the synergistic influence of phytoconstituents in green copper nanoparticles (g-Cu NPs) using Hagenia abyssinica leaf extract from Ethiopia. The g-Cu NPs were characterized using various techniques, including UV-visible, UV-DRS, FT-IR, XRD, SEM, EDXA, TEM, HRTEM, and SAED. The g-Cu NPs showed a mix of spherical, hexagonal, triangular, cylindrical, and irregularly shaped Cu particles, with an average particle size of 34.76 nm. The antibacterial tests on E. coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Bacillus subtilis showed good zone of inhibitions, indicating potential as a remedy for infectious diseases.[2] Researchers are exploring eco-friendly and low-cost methods for biosynthesis of nanoparticles (NPs). A study involving copper oxide (CuO) NPs was conducted using a copper nitrate trihydrate precursor[3] and Catha edulis leaves extract. The NPs were characterized using various techniques, including X-ray diffractometer, SEM-EDS, TEM, UV-Vis, and FTIR. The study also tested the antimicrobial activities of different concentrations of CuO NPs using Catha edulis extract, with the highest zone of inhibition observed for S. aureus, S. pyogenes, E. coli, and K. pneumonia. This study synthesized copper nanoparticles (CuNPs) using mint extract. Various spectroscopy, X-ray diffraction, and Fourier transform infrared spectrometry were used to characterize the NPs. The NPs were found to have a spherical shape and showed a condition- dependent effect on wheat growth.[4] The maximum germination and growth rate were observed at 50 mg CuNPs/L, while growth declined beyond this concentration. The application of CuNPs improved wheat growth. This review provides an overview of the classification, characterization, preparation, and application of nanoparticles, focusing on their properties, synthesis, and applications. It highlights the importance of controlling shape, size, and composition to enhance nanoparticles' properties, including enhanced surface area, unique optical, electronic, and magnetic characteristics, and improved mechanical properties.[5] Nanoparticles have applications in catalysis, environmental remediation, and antimicrobial coatings, contributing to sustainable development and environmental protection. The review serves as a reference for understanding the field's latest research and developments.

Keywords: Nanoparticles, Electron microscopy, Green synthesis, C.longa, Cu nanoparticles, Pathogenic activity.[1]