POLYCYSTIC OVARIAN SYNDROME AND HYPOTHYROIDISM

Safa M. Khalafalah*, Maryam M. Bisher, Abdalhakeem A. Melad and Mohammed A. Yuones

ABSTRACT

Introduction: As the prevalence of these endocrine dysfunctions increases, the association of polycystic ovary syndrome (PCOS) and thyroid disease is increasingly being recognized. Objective: This study aimed to find out the relationship between hypothyroidism and polycystic ovary syndrome. Materials and Methods: This study was conducted on a sample of women who suffer from low fertility and hypothyroidism, attending to some health clinical serves in the Brak Al-Shati area from 1st of July 2021 to the end of December 2022. 60 women were participating in this study, they were divided in to: 1. patients' group 40 women (hypothyroidism and PCOS) and control group 20 healthy women. The ages of the women participating in the study were between 18 and 45 years. Results: PCOS was found to be more prevalent in participants with hypothyroidism (65% vs. 35%). Increased BMI (28.53 ± 5.05 kg/m2 vs. 23.20 ± 2.18 kg/m2; p-value: <0.05) and increased TSH was significantly more in participants with PCOS. Conclusions: This study concluded that there is an association between hypothyroidism and PCOS. Therefore, PCOS patients must be screened with a thyroid profile.

Keywords: Hypothyroidism, Thyroid Stimulating Hormone, Prolactin, Polycystic Ovary Syndrome.