EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia ,

ISSN 2394-3211

Impact Factor: 7.065

ICV - 79.57

Abstract

CHANGES IN CELLULAR AND HUMORAL IMMUNITY IN PREGNANT WOMEN INFECTED WITH COVID-19

*Musakhodjaeva Diloram A., Eshimbetova Gulsara Z., Mukhamedova Barno U., Azizova Zukhra Sh., Rustamova Nazokat B. and Kurbanova Sanobar Y.

ABSTRACT

According to the literature, pregnant women are more susceptible to coronavirus infection due to changes in their bodies, especially in the respiratory and immune systems. The aim of this study was to examine the cellular and humoral factors of adaptive immunity in pregnant women infected with COVID-19. Eighty-five pregnant women at 33-37 weeks of gestation with confirmed COVID-19 diagnosis were examined. They were divided into two groups based on the severity of COVID-19: 56 women with moderate severity and 29 women with severe disease. The number of cells with phenotypes CD3, CD4, CD8, CD16 in peripheral blood, and levels of IgA, IgG, and IgM in serum were studied using the ELISA method. It was found that pregnant women with COVID-19 show a severity-dependent imbalance in the studied parameters of cellular and humoral immunity.

Keywords: COVID-19, pregnant women, cellular and humoral immunity.

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