THE ROLE OF PLATELET-RICH PLASMA INJECTIONS INTO THE OVARY IN IMPROVING OVULATION

Mais Hassan*, Ahmad Abd el Rahman and Lina Ramadan

ABSTRACT

The research aimed to evaluate the effectiveness of intraovarian platelet-rich plasma injections in improving ovulation in infertility patients who suffer from ovarian insufficiency (high FSH value), decreased ovarian reserve (low AMH value), or polycystic ovaries (high AMH value). (40) female patients of reproductive age were admitted to the women's clinic at Tishreen University Hospital, who were suffering from infertility due to premature ovarian insufficiency, low ovarian reserve, or dysovulation due to polycystic ovary syndrome. The necessary general and hormonal analyses were performed, as well as ultrasound imaging of the uterus and appendages to diagnose the condition, and a semen analysis of the husband was performed (provided that it was normal). The patient was prepared for laparoscopy in order to inject platelet-rich plasma after the end of the menstrual cycle in the first phase of the cycle. (10) ml of platelet-rich plasma was prepared from the blood of the concerned patient, and (5) ml was injected into each ovary through one puncture, and the improvement of ovulation was monitored by ultrasound imaging and hormonal analyses three months after the injection. The research results showed that platelet-rich plasma injections are a promising treatment for infertility patients, as this treatment can help improve fertility and women’s general health. The evidence for this is that (69.23%) of the patients suffering from ovarian insufficiency had an improvement in ovulation after the injection procedure, and the significance of the FSH values three months after the injection indicates its return to normal values compared to its values before the injection, which indicates an increase beyond the limits Natural. Also, (53.33%) of the patients with low ovarian reserve had an improvement in ovulation after the injection procedure, and the significance of the average AMH value after the injection indicates that it has increased and returned to normal values compared to its values before the injection, which indicates that it is outside the normal limits. In addition, (58.33%) of the total patients who had polycystic ovaries had an improvement in ovulation after the injection, and the significance of the AMH value after the injection indicates its decrease and return to normal values.

Keywords: Platelet-rich plasma, ovarian insufficiency, low ovarian reserve, polycystic ovary.